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Goldstein et al., 2012 Found rapid decrease in swelling and immune-mediated tissue damage

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However, there is compelling evidence that caspase-3 and caspase-8 are downstream effectors of the Fas cell death signaling pathway, indicating their importance for extrinsic Fas-mediated eryptosis (see the Extrinsic Fas-mediated eryptosis section) [130, 136]