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The headline results at 80 weeks were: 12 mg dose: average weight loss of 28.3% (approximately 70.3 lbs / 31.9 kg) 9 mg dose: average weight loss of 25.9% (approximately 64.4 lbs / 29.2 kg) 4 mg dose: average weight loss of 19.0% (approximately 47.2 lbs / 21.4 kg) Placebo: average weight loss of just 2.2% Perhaps most striking was the proportion of patients hitting bariatric-surgery-level outcomes: at the highest dose, 45.3% of participants lost 30% or more of their body weight , and 65.3% reduced their BMI to below 30 kg/m meaning they were no longer classified as living with obesity by the end of the trial

Additionally, these effects extend to key adiposity markers, creating a consistent pattern of metabolic improvement across controlled research settings

LP3-R is used in controlled laboratory environments to study triple receptor interactions and downstream signaling mechanisms

Weight Loss Pens: GLP-1 and GIP pen protocols are medically guided and reviewed by registered UK healthcare practitioners under corresponding regulatory mandates.

PlexusDx offers compounded semaglutide and tirzepatide through its Weight Management Protocols