It mirrors the impact we have seen from statins, ace inhibitors, and beta-blockers in similar populations and generally those studies have had a longer treatment duration meaning that semaglutide could be a far superior intervention at the 5 year mark
Metformin has been shown to improve insulin sensitivity, which causes our cells to be more responsive to insulin
J Obesity 28(6):10501061 Garvey WT, Batterhazm RL, Bhatta M, Buscemi S et al (2022) Two years effects of semaglutide in adults with overweight or obesity: the STEP 5 trial
[DOI] [PubMed] [Google Scholar] 65.European Medicines Agency
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