The key is being honest about the tradeoffs
In practice, it often leads to: Loss of strength Reduced muscle mass Poor workout recovery Fat loss plateaus Carbs help preserve muscle
The clinical picture the alert describes is specific: abnormal liver function tests showing transaminitis with possible raised bilirubin and coagulopathy. In plain terms, the liver enzymes that leak into the blood when liver cells are dying were elevated, the pigment the liver is supposed to clear was building up, and the blood was losing its ability to clot, which is what happens when a liver stops making the proteins that hold clotting together
While LBM loss appears to be less pronounced than FBM loss in many studies, the clinical significance of even modest reductions in skeletal muscle remains uncertain, particularly in older adults or individuals at risk of sarcopenia
The MHRA advises reporting any suspected adverse reactions via the Yellow Card Scheme (yellowcard
But note that those are the parameters for the general public and your doctor will likely tailor the recommendations specifically to your case