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Conversely, as drug pressure subsides or microenvironmental cues shift, DTPs can reactivate stemness programs and re-enter the cell cycle, giving rise to relapsed tumors [82]

The study also showed that GHK-Cu was able to decrease the production of IL-6 and TNF-1 while increasing the activity of superoxide dismutase by blocking the activation of NFBs p65 and p38 MAPK