Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (/) mice
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S is a key protein in the pathology of Parkinsons disease (PD) [253], characterized by the loss of dopaminergic neuronal cells in the substantia nigra pars compacta and the abnormal accumulation and aggregation of S in the form of Lewy bodies and Lewy neurites
This variation relates to tissue-specific expression of NRK1 (found everywhere) and NRK2 (mainly in cardiac and skeletal muscles) [4]
doi: 10.1016/bs.afnr.2017.11.001 37 TylickiASiemieniukM