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In transgenic FVB/N mice overexpressing the human HER-2/neu (erbB-2) oncogene, Epithalon administration results in a significant reduction in HER-2/neu mRNA levels, with a reported 3.7-fold decrease relative to saline controls

The GI side effects, while potentially improved with BPC-157 support, may still occur

Simultaneously, they suppress glucagon secretion (which normally raises blood glucose), slow gastric emptying to reduce post-meal glucose spikes, and act on appetite centres in the brain to promote satiety and reduce food intake

(2022) 20:e200916

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