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The CNS is particularly vulnerable to oxidative damage due to its high oxygen consumption, abundance of polyunsaturated fatty acids, and relatively low levels of antioxidant enzymes [158]

Plant secondary metabolites as modulators of mitochondrial health: an overview of their anti-oxidant

A number of studies have shown that oxidative stress increases with aging, and leads to degenerative diseases, like heart disease, cancer, diabetes, and more

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J Biol Chem 285:1252212535 [DOI] [PMC free article] [PubMed] [Google Scholar] Morgan MM, Christie MJ

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