Glucagon-like Peptide-1 Receptor (GLP-1R) Signaling: Making the Case for a Functionally Gs Protein-Selective GPCR, Lymperopoulos A
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This class of compounds binds to key receptors in the brain, pancreas, and gastrointestinal (GI) tract, instigating several biological reactions: Enhances insulin secretion Slows gastric emptying Increases -cell proliferation Reduces glucagon release Mitigates hunger signaling These actions combine to regulate appetite, food intake, and the physical feeling of fullness (satiety)
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