A: Short-term weight loss may temporarily improve climbing or running economy, but rapid loss of lean mass, chronic under-fuelling and impaired recovery can ultimately reduce long-term performance
Breastfeeding mothers who need to manage their diabetes or chronic weight loss may opt for insulin, metformin, dietary adjustments, and consistent physical activity
Liu W, Jalewa J, Sharma M, et al
3 Endocrine ReviewsGrowth hormone secretagogues: mechanisms of action and clinical applications
Assists with regeneration of vitamins C and E*
The correct classification: Pure GLP-1 agonists: exenatide, liraglutide, lixisenatide, dulaglutide, semaglutide, efpeglenatide, orforglipron Dual GIP/GLP-1 agonists: tirzepatide Triple agonists (GIP/GLP-1/glucagon): retatrutide Retatrutide, approved in early 2026, adds glucagon receptor agonism to the dual GIP/GLP-1 mechanism