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Targeting TMAO is a potential strategy for CVD therapy

There is no universal best for every individual but from a receptor-complexity perspective, triple agonists currently represent the most advanced metabolic approach under investigation

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Glycine provides antioxidant support, anti-inflammatory effects, modulates the immune system, and promotes collagen synthesis

Kauser S, Thody AJ, Schallreuter KU, Gummer CL, Tobin DJ

32 Importantly, recently developed long-acting GLP-1 analogs have been demonstrated to target multiple brain nuclei, including the hypothalamus, thereby expanding the therapeutic potential of GLP-1-based interventions 36,46 (See Figure 1)