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What the Latest Clinical Trial Results Show According to publicly reported late-stage trial data: Participants receiving higher doses achieved average weight loss approaching 2530% over approximately 68 weeks Some individuals lost more than 70 pounds during the study period Participants with obesity and knee osteoarthritis also reported significant reductions in joint pain These outcomes exceeded the average weight loss typically reported in clinical trials of currently approved GLP-1 medications
Apr 2023;23(4):520-530
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Additionally, GLP-1 RA users showed a reduced risk of major adverse cardiovascular events (MACEs), such as heart attacks and strokes
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