retatrutide trial status 9 mth clinical update (TRIUMPH-3) : r/RetatrutideTrial Retatrutide Severe Obesity Trial Shows

It remains an investigational compound available for laboratory research only

Kennedy, Jr

With the evolving evidence and guidelines across the world, we should now choose second-line agents such as SGLT2i and GLP1-RAs with proven CV benefits in patients with high CV risk followed by agents with proven CV safety if additional glycemic control is required

For patients with MASLD, this means mazdutide could serve double duty: treating obesity while simultaneously addressing the liver disease that often accompanies it

Oral semaglutide is a tool, not a magic wand

Education, follow-up, dose adjustments, nutrition, and accountability often make the greatest difference. Dr