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However, response may vary: Higher baseline weight Individuals starting at higher body weights may experience: Slower percentage weight loss initially Need for full maintenance doses to achieve optimal effects Potentially better tolerance of higher doses Lower baseline weight Those with lower starting weights might: Achieve therapeutic goals at submaximal doses (e.g., 2.4 mg vs

Regulation of NF-B by TNF family cytokines

Hydroxocobalamin provides a longer-acting effect compared with oral B12 supplements, which reduces the frequency of dosing

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But feeling better right away does not mean the body is fully healed