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Indeed, GCG antagonists, developed as potential glucose-lowering therapies, were associated with an increase in hepatic steatosis [38], suggesting that GCG agonists may reduce hepatic steatosis [39]

Nash, C

This phenomenon underscores a critical principle that the biological effects of a given nanomaterial can be profoundly divergent, even opposite, across different pathological contexts, highlighting a strong microenvironment-dependent functionality

488,489,490 These inhibitors are capable of specifically targeting categories, subtypes, and structural domains, 491 potentially providing more pronounced benefits in terms of efficacy, safety, and tolerability

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