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Since 2016, multiple scientific journals have established a connection between Ozempic and acute gallbladder disease, gallstones, and inflammation

Utilizing its proprietary Artificial Intelligence-assisted Structure-Based Drug Discovery (AISBDD) and Ultra-Long-Acting Platform (ULAP) technologies as well as Peptide Oral Transport ENhancement Technology (POTENT), Ascletis has developed multiple drug candidates in-house, including both small molecules and peptides, such as its lead program, ASC30, a small molecule GLP-1R agonist designed to be administered once daily orally and once monthly to once quarterly subcutaneously as a treatment therapy and a maintenance therapy for chronic weight management

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Weight loss of approximately 25% was maintained for up to ten years post-surgery

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No new safety concerns were identified for IcoSema in this trial, and the safety profile for IcoSema reflected that of the respective mono-components