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DOI: 10.1172/JCI194740,

GLP-1 signaling also directly downregulates proinflammatory cytokines in mucosal immune cells (55), consistent with a targeted hierarchy of mechanisms that prioritizes epithelial defense and local immune modulation over systemic immunosuppression

Khansai et al

Introduction Diabetes is a chronic metabolic disease characterised by persistent hyperglycemia, which affects multiple organ systems and leads to various complications [1]