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Instruments such as the Pooled Cohort Equations (PCE) of the American College of Cardiology (ACC)/AHA, the Framingham General Cardiovascular Risk Profile for primary care, the Systematic Coronary Risk Evaluation (SCORE), the AHA Predicting Risk of Cardiovascular Disease Events (PREVENT), the European Systematic Coronary Risk Estimation 2 (SCORE2), and the Systematic Coronary Risk Estimation 2Older Persons (SCORE2-OP) risk calculators are widely available to estimate 10-year cardiovascular risk [Table 2] [15]