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doi: 10.1371/journal.pntd.0010724 46 JulienJLeparc-GoffartILinaBFuchsFForaySJanatovaIet al

Hormonal Imbalances Growth hormone-related peptides , such as GHK-Cu or CJC-1295 , can disrupt the bodys endocrine system if used excessively or without medical oversight, leading to side effects ranging from fatigue and mood changes to more severe imbalances

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Similarly, clinical studies have shown that appropriate selenium supplementation in selenium-deficient individuals enhances GPx4 activity, prevents cell ferroptosis, and thus prevents the occurrence of IBD [278]

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Furthermore, biomarker-driven patient stratification should be integrated into clinical trial designs to identify patients most likely to benefit from CSC-directed therapies