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As mentioned above, ferroptosis could be induced to exert anti-tumor functions via signaling pathway modulation, non-coding RNA expression, DNA methylation, histone modification, CSCs, microenvironment remodeling, and so on
Intestinal absorption and cellular transport depend on transporters (e.g., OCTN2 ) and the kidney reabsorbs much of it to maintain levels
Weight maintenance strategies for patients on pharmacological therapy for obesity. The Journal of Clinical Endocrinology & Metabolism
However, the FDA requires a boxed warning for thyroid C-cell tumors based on rodent studies, though human relevance remains uncertain
Evidence includes laboratory, animal, and limited human studies