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In contrast, it has been shown that overexpression of FLNA inhibited cell motility (92) and FLNA knockdown promoted cell migration, invasion, and metastasis (93, 94), leading to the conclusion that FLNA positive or negative effect on cell motility depend on the cell type and on a balanced level of FLNA expression

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The major reasons for cancer therapy failure include detection of the disease and resistance to chemotherapeutic agents used in clinical practice

(2017) IGFBP-2 and IGF-1 LR3 in GLUT-4 Translocation in 3T3-L1 Adipocytes Oxid Med Cell Longev