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2021 Jul 26;13(8):2550

[6] [7] [10] GPx1 typically uses glutathione (GSH) as the reductant, but when glutathione synthetase (GSS) is, as in brain mitochondria, -glutamylcysteine can serve as the reductant instead

Briefly, cells were seeded (1 10 5 cells/well) in a 12-well plate overnight before treatment with various agents in serum-free medium condition

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It has been shown that alveolar epithelial lining fluid of patients with ARDS is deficient in total GSH compared to normal subjects (107), and neutrophil-mediated oxidants release leads to GSH deficiency and lung cell injury (107)

Carnitine for the treatment of idiopathic asthenospermia: a randomized, double-blind, placebo-controlled trial