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The most practical approach for many protocols involves starting with a 5mg vial for the early escalation phases and switching to a 10mg vial once weekly doses are higher

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After gentle facial cleansing, a topical eutectic mixture of local anesthetic cream application was applied over the area to be treated and left for about 45 to 60 minutes

Xue et al., 2023), further supporting the role of this class of molecules in modulating cancer cell behavior