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Furthermore, the long-term safety profile of BCKDK inhibitors in humans, optimal dosing windows, tissue-specific off-target effects, and patient-specific contraindications remain to be established in adequately powered and duration-sufficient clinical trials

Refrigerate as soon as possible, and this window should only be relied upon during unavoidable circumstances like delayed luggage or broken cooling equipment

Scalavino, V

There are many oral and injectable options now that are FDA-approved, so its best to stick with medications that have been assessed by the standard safety/efficacy channels

Davis L, et al

Hims & Hers and its surrogates objected