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The peptide carries a C20 fatty diacid attached via a -glutamic acid spacer at lysine-20, which mediates albumin binding and confers an extended pharmacokinetic half-life of approximately six days in preclinical research models, as characterized in published phase 2 pharmacokinetic work

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Less common but more serious side effects include pancreatitis (severe or persistent stomach pain, with or without vomiting), gallbladder problems (strong pain after meals, or yellowing of the skin or eyes), increased resting heart rate, and kidney problems