oral versions require daily administration and careful attention to food timing
As discussed, the anti-hyperglycaemic effects of DPP-4 inhibition are mediated via enhancing levels of endogenous DPP-4 substrates, since the inhibitors themselves do not possess any inherent glucose-lowering activity
In a study where subjects underwent esophageal sampling along with a validated food frequency questionnaire to quantify dietary fiber and fat intake, findings showed that increased fiber intake was significantly associated with increased relative abundance of thick-walled phyla and decreased relative abundance of overall G- bacteria, including Prevotella, Neisseria , and Eikenella ( 22)
American Lung Association/American Thoracic Society International Conference
Effect of DPP-4 inhibitors on microvascular events in landmark trials An adequate assessment of the effect of antidiabetic drugs on the risk of microvascular events requires trials that evaluate durations of glucose-lowering treatments administered for a decade or longer
Hes a well-respected doc in this field
