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GLP-1 receptor agonists have transformed weight management for millions, with clinical trials showing average losses of 15-22% body weight

You might fall asleep faster, but deep sleep and REM sleep are both significantly reduced

Gradual titration: prescribers usually start low to improve stomach-related tolerability

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This has direct implications for research design: studies examining physiological GH patterns favor secretagogues, while studies requiring controlled supraphysiological GH levels use exogenous HGH

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