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Materials and methods The experimental protocol was approved by the Mansoura University Animal Care and Use Committee (MU-ACUC), approval code: MU-ACUC (MED.PhD.23.06.2)

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These maleimide functional groups play dual roles, that permitting a Toll-like receptor 2 binding peptide conjugation in order to improve cancer cell specific delivery, in the other hand, once in cytosol, maleimide efficiency improve oridonins redox imbalance promoting ability by simultaneous GSH depletion

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It facilitates excretion of these harmful compounds from the body, and low levels of GSH have been linked to chronic exposure to chemical toxins that lead to things like macular degeneration, Parkinson's disease, and other neurodegenerative disorders

Insulin resistance is seen in around 4470% of women who have been identified with PCOS [52]