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The closest data: REDEFINE 1's 6.6-percentage-point gain from layering cagrilintide on semaglutide

The difference is printed on a small label that is easy to misread or overlook

Additional documentation may be required showing why the commercial product cannot be used

That lack of approval matters

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Potential insulin sensitivity changes While no direct evidence suggests a negative effect on blood sugar, some peptides may affect insulin signaling over time