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-MSH Analog Cyclic Heptapeptide University of Arizona Originator Literature Reported Mechanism (Literature) Non-Selective Melanocortin Receptor Agonist Pan-MCR activation (MC1R, MC3R, MC4R, MC5R) Al-Obeidi and colleagues (1989, PMID 2555512) designed Melanotan II as a non-selective melanocortin receptor agonist with 100-fold enhanced melanotropic potency versus -MSH in the lizard skin bioassay

Instead, it creates conditions where fat becomes easier to mobilize and eliminate

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Available as: Last cited 8 Sept 2023 Ethics declarations Ethics approval and consent to participate Since it is a review article, they are not required

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Unlike full-length growth hormone or growth hormone secretagogues, it provides lipolytic benefits without affecting IGF-1 levels, glucose metabolism, or growth-promoting effects