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Of the four crossover RCTs assessed, three studies raised some concerns about the Randomization process (D1) (41, 46, 50), and one study showed bias issues caused by menstruation and carryover effects (DS) (41)

This decentralization has created a patchwork of policies: some states cover GLP-1s for diabetes only, others for both diabetes and obesity, and a few restrict coverage to specific patient populations or BMI thresholds

Sources: [1] Raun K, et al

American Family Physician, 72(7), pp.12851292.

Molecular: peptide stability and extended half-life through DAC binding

[11] Brand-Miller et al., (2002) Glycemic index and obesity, The American Journal of Clinical Nutrition, Volume 76, Issue 1, Pages 281S-285S, ISSN 0002-9165, ajcn/76.1.281S