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The induction of genes encoding a sodium inducible calcium binding protein, a protein phosphatase, a PAL and GSTF7 were observed (Naidoo et al., 2007)

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Their dual mechanismsmicrobiota regulation and barrier enhancementinclude stimulation of beneficial bacteria such as Lactobacillus and Bifidobacterium , elevation of SCFA production (e.g., butyrate as an epithelial energy source, acetate for Treg differentiation), inhibition of TLR4/NF-B inflammatory signaling, and activation of the Nrf2/HO-1 antioxidant pathway

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