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[8] Untreated, and over years to decades, CTS causes loss of sensitivity, weakness, and shrinkage (atrophy) of the thenar muscles at the base of the thumb

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However, the results of A Long Term Evaluation (LEADER) trial that followed for 3.5-5 years showed no effect of GLP-1 receptor activation on human serum calcitonin levels, C-cell proliferation or C-cell malignancy (15)

The reaction mixture was retrotranscribed at 48 C for 45, denatured for 2 at 94 C and then subjected to 1826 cycles of denaturation for 30 seconds, annealing at 55 C for 45 seconds, and elongation at 68C for 1 minute

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