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Indeed, genetic deletion of Nrf2 in keratinocytes rescues Keap1-KO mice from lethal hyperkeratosis [69]

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For metabolic analysis of cultured cancer cells and tumours, frozen tumour tissue was homogenized in 80% methanol containing 20 mM NEM using a Precellys cold tissue homogenizer (Bertin) at a ratio of 20 mg tissue to 1 ml solvent

It should also be noted that not only glutaredoxin can participate in these processes [64,65]

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(2017) pointed out that pharmacological inhibition of autophagy by 3-methyladenine enhanced mitochondrial dysfunction and tubular apoptosis during CP treatment