Medicare announced the pilot program for the popular weight loss medications on Wednesday
The label was updated with clinical trials data that supporting its effectiveness and safety for the longer period of use
Most adults should aim for: Women: at least 25 grams of fibre per day Men: at least 38 grams of fibre per day If your current intake is much lower, like the vast majority of the population, increase fibre gradually over several weeks and drink plenty of water to help prevent digestive discomfort
Dosing in the Phase 3 Diabetes Trial (TRANSCEND-T2D-1) A1C reduction: -1.7% to -2.0% across doses (from baseline 7-9.5%) Weight loss at 12 mg: 16.8% (-36.6 lbs) at 40 weeks Discontinuation due to adverse events was relatively low across all doses, similar to the patterns seen in TRIUMPH-4 The diabetes population typically loses less weight on GLP-1 drugs than the obesity-only population, which is consistent with what was observed: ~17% weight loss in T2D vs
Phase 2 trial dosing groups explained The trial randomized participants into seven groups
Within a year, he lost 30 more pounds, stopped one blood pressure medication, and reached an A1C of 5.5%
