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Room Temperature (around 68-77F or 20-25C): This is where they're most vulnerable

This patient exhibited nuclear and lamellar opacities, developmental delay, spastic hemiparesis, and cryptogenic neonatal cirrhosis, suggesting a broader pathogenic role for CYP51A1 mutations beyond isolated cataract formation [81]

It is also found in Xuzhou and Shanghai but it is less frequent in Beijing and Vietnam.7,8,12 Interestingly, the same nonsense mutation was found as far as in Western Asia countries including Lebanon, Turkey and Saudi Arabia (Figure 2)

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Dose-dependent response: Higher doses produced greater and more sustained GH and IGF-1 elevations