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[DOI] [PMC free article] [PubMed] [Google Scholar] 271.Al Ghafli M., Padmanabhan R., Kataya H., Berg B

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(PubMed) Heude B, Ducimetiere P, Berr C

Persistent accumulation of misfolded proteins triggers a cellular stress response and, if unresolved, leads to cell death

The p62-Keap1-NRF2 pathway plays an important role in preventing ferroptosis in HCC cells, and the RAS/Raf/MEK pathway is an important target for the treatment of HCC 32,40