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Name: what is glp-1 drugs medications get at the heart of addiction: study – WashU Medicine GLP-1 Receptor Agonists | New
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PMID 12654482

Specifically, the protein ankyrin repeat and SOCS box protein 1 (ASB1) (a substrate-recognition subunit of an E3 ubiquitin ligase complex) binds to SQOR and mediates K48-linked ubiquitination of SQOR, targeting it for proteasomal degradation