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Vecchio LM, Meng Y, Xhima K, Lipsman N, Hamani C, Aubert I

Approximately 40% of colon cancer patients have KRAS mutations, and patients with KRAS G13D have a poor prognosis, including susceptibility to metastasis and short survival time, while anti-EGFR therapy offers little benefit

Complexation Following synthesis, the peptide is complexed with copper(II) ions under controlled conditions to form GHK-Cu

The mechanism involves IGF-1-mediated stimulation of osteoblast proliferation and enhanced collagen synthesis in bone matrix

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