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Peer review Peer review information Nature Reviews Rheumatology thanks Maria Sole Chimenti, Rubn Queiro and Eric Toussirot for their contribution to the peer review of this work

This delay can lead to symptoms such as: Nausea Vomiting Early satiety (feeling full quickly) Bloating Abdominal discomfort Depending on the severity, gastroparesis can eventually cause malnutrition and other serious health concerns

Advertencia importante sobre tumores tiroideos: Tirzepatide tiene una advertencia de recuadro negro sobre el riesgo de tumores de clulas C tiroideas, incluido el carcinoma medular de tiroides

The article names uncontrolled diabetes, a history of pancreatitis, and kidney disease as conditions requiring close monitoring even during routine dosing, and by extension during any interruption

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14.3 Patients with Gastrointestinal Disorders Underlying gastrointestinal conditions may be exacerbated