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After symptoms resolve, a slower re-escalation can be attempted, perhaps increasing by smaller increments than the standard protocol specifies

115 Additionally, intracellular signaling components such as -catenin (Wnt pathway) and Gli1/2 (Hedgehog pathway) are also important for CSC survival and proliferation

The informal designation references the fictional character's accelerated tissue repair as a colloquial analogy for the multi-pathway recovery research focus