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For patients switching from tirzepatide to semaglutide or other weight loss agents, the 35-day clearance window provides a logical washout period between medications

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-OHB injections in healthy adults reduce leucine oxidation and enhance the incorporation of leucine into the skeletal muscles (72)

Importantly, the early trials in humans (e.g

10.1210/en.2012-1937 [DOI] [PubMed] [Google Scholar] 169.Grundy SM