These isogenic, mutation-specific cell lines have become a crucial tool for the pre-clinical screening and development of mutation-specific CFTR modulators (Valley et al., 2019)
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Durable efficacy of liraglutide in patients with type 2 diabetes and pronounced insulin-associated weight gain: 52-week results from the Effect of Liraglutide on insulin-associated wEight GAiN in patients with Type 2 diabetes (ELEGANT) randomized controlled trial
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While these radicals are essential for pathogen clearance, excessive or chronic inflammation can lead to tissue damage due to the persistent high levels of free radicals [58]
Body composition and metabolic alterations: diagnosis and management