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While headaches arent considered a common side effect of tirzepatide (the active ingredient in Zepbound and Mounjaro ), some people report experiencing tirzepatide headaches during treatment

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Moving forward, future studies are needed to understand the side effects and safety of long-term GLP-1 use

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Ideally, wrote Davis in a follow-up email, the government agency will spell out its specific concerns about each peptide, and then describe what data would be needed for the FDA to overturn its prohibitions