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It also has a real downside: roughly 40 percent of patients in the clinical trials reported nausea, with a meaningful number needing anti-nausea medication or stopping treatment because of it

ApoE 4 activates LRP1 less than other ApoE isoforms [66]

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The research, published on November 13 in The study, which included around 228,000 people in Sweden, showed a 36% lower risk of hospitalization among those taking semaglutide

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The higher rate of kidney stones, for instance, might not be due to something the drug is doing but rather because people taking it have a lower appetite and struggle to drink enough fluids