And for patients who do eventually have surgery, GLP-1s are increasingly part of the picture before and after
& nler-Gmta, A
Semaglutide also has a longer half-life than the older GLP-1s and may have a stronger effect on receptors in the brain, which could help explain the difference in findings, Moreno adds
Healthcare providers usually recommend waiting 46 weeks before making any changes to your treatment plan
How Trulicity works Trulicity mimics one hormone called GLP-1 (glucagon-like peptide-1), which: Slows food movement through your stomach, helping you feel fuller for longer Communicates with your brains appetite centre to reduce hunger Improves blood sugar control by enhancing insulin function How Mounjaro works Mounjaro activates two hormone receptors: Like Trulicity, it activates the GLP-1 receptor It also activates GIP (glucose-dependent insulinotropic polypeptide), a second gut hormone involved in appetite and blood sugar regulation This dual-action is the primary reason Mounjaro produces greater weight loss and blood sugar improvements than GLP-1-only medications like Trulicity
Yau K, Odutayo A, Dash S, et al
