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ISHR 11.-14.06.2024 Toulouse, Abstractbook (sciencesconf.org:ishr2024:538288) Packer M, Zile MR, Kramer CM, Baum SJ, Litwin SE, Menon V, Ge J, Weerakkody GJ, Ou Y, Bunck MC, Hurt KC, Murakami M, Borlaug BA, SUMMIT Trial Study Group (2024) Tirzepatide for heart failure with preserved ejection fraction and obesity
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we also examined the incidence of individual components of MACEs, including cardiovascular death, non-fatal myocardial infarction, non-fatal stroke, and hospitalization for heart failure
The ARB works to ease the tension in blood vessels while the diuretic aids in eliminating surplus water and salt from the body
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However, as doses increase, tirzepatide's dual-action effect can trigger nausea in up to 30% of patients, so early tolerance does not guarantee later comfort
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