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2005;90(3):F281-282

For hair , it is a reasonable add-on but not a first-line treatment

Contrarily, a study with 8 GH-deficient subjects found that IGF-1 administration increased lipid oxidation (being this effect more potent when co-administered with GH), energy expenditure, and insulin resistance [108, 183]

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Growth hormone therapy can induce insulin resistance, elevate fasting glucose, worsen glycemic control in diabetics or pre-diabetics, increase risk of developing type 2 diabetes with long-term use, and require medication adjustments for individuals with existing diabetes

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