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Administering GLP-1 ICV into the hindbrain reduced feeding [71] and increased nausea [72]

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The two medications work through entirely different mechanisms and do not interfere with each other pharmacologically

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Autism spectrum disorder is associated with deficits in the ontogeny of neural circuits (Geschwind and Levitt, 2007)

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Some manufacturers have responded to the broader pricing pressure environment by explicitly shifting their R&D portfolios toward orphan indications

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In the gastrointestinal system , these medications slow gastric emptying and reduce appetite through central nervous system pathways, contributing to weight loss

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